Sperm Coating Mechanism from the 1.8 Å Crystal Structure of PDC-109-Phosphorylcholine Complex
نویسندگان
چکیده
منابع مشابه
Interaction of PDC-109, the major secretory protein from bull seminal vesicles, with bovine sperm membrane Ca2+-ATPase.
PDC-109 is the prevalent secretory protein from bovine seminal vesicles that binds to the midpiece of sperm once they pass the ampulla of the vas deferens during emission. Thereby, the protein changes biophysical membrane properties, eventually resulting in increased sperm motility. To elucidate the underlying biochemical mechanism, we have studied the ion-pumping activity (Ca(2+)-ATPase) in me...
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ژورنال
عنوان ژورنال: Structure
سال: 2002
ISSN: 0969-2126
DOI: 10.1016/s0969-2126(02)00751-7